cb1 agonist 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T62761	CB1 agonist 1		Cannabinoid Receptor
	CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.		Cannabinoid Receptor
T10694	CB1 inverse agonist 1	MRL-650	Cannabinoid Receptor
	CB1 inverse agonist 1 (MRL-650) is an orally active and selective CB1 agonist. The IC50s for CB1 and CB2 are 7.5 nM and 4100 nM, respectively. CB1 inverse agonist 1 shows anorexigenic effects.		Cannabinoid Receptor
T62468	CB1/2 agonist 1
	CB1/2 agonist 1 is a potent CB1/2 agonist that crosses the blood-brain barrier, acting on CB1R (EC50: 56.15 nM) and CB2R (EC50: 11.63 nM). CB1/2 agonist 1 reduces glutamate release and LPS-induced microglia activation, a...
T13080L	Taranabant	MK-0364	Cannabinoid Receptor
	Taranabant (MK-0364) is a selective and potent cannabinoid 1 (CB1) receptor inverse agonist used in the study of obesity and nicotine dependence.		Cannabinoid Receptor
T12306	OMDM-5		Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel
	OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM).
T1915	AM251		Cannabinoid Receptor , GPR
	AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 nM).		Cannabinoid Receptor , GPR
T1519L	Rimonabant	SR141716	Cannabinoid Receptor , Antibacterial , Acyltransferase
	Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue of effect is a reduction in appetite. Rimonabant...		Cannabinoid Receptor , Antibacterial , Acyltransferase
T28657	SAD-448
	SAD-448 is a cannabinoid receptor type 1 (CB1) agonist. SAD-448 controls spasticity via action on the peripheral nerve CB1 receptor.
T27803	LBP-1	LBP1
	LBP-1 is a cannabinoid receptor type 1 (CB1) agonist.
T61736	CB1/2 agonist 3
	CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a competitive agonist for the CB1/CB2 receptors. It exhibits CB1/CB2 agonistic activity by binding to the human CB1 and CB2 receptors, with Ki ...
T62180	CB1/2 agonist 2
	CB1/2 agonist 2 (compound 23) is a potent non-selective cannabinoid ligand with Ki of 3.5 nM and 1.2 nM, respectively. CB1/2 agonist 2 is a full agonist of CB1 and a competitive inverse agonist of CB2. BACE-IN-1 is a com...
T13081	Taranabant racemate	MK-0364 racemate	Cannabinoid Receptor
	Taranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor.		Cannabinoid Receptor
T14504	BAY 38-7271		Cannabinoid Receptor
	BAY 38-7271 has strong neuroprotective properties.[1] BAY 38-7271 is selective and highly potent and cannabinoid CB1/CB2 receptor agonist. With Kis of 1.85 nM and 5.96 nM for recombinant human CB1 receptor and CB2 recept...		Cannabinoid Receptor
T61849	AM8936
	AM8936 is a well-balanced and highly potent agonist for the cannabinoid receptor type-1 (CB1) in functional assays, with EC50 values of 8.6 nM and 1.4 nM for the rat CB1 (rCB1) and human CB1 (hCB1) receptors, respectivel...
T78083	CB-25		Cannabinoid Receptor
	CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cells [1].		Cannabinoid Receptor
T11834	Leelamine hydrochloride		Others
	Leelamine hydrochloride, a tricyclic diterpene extracted from pine tree bark, inhibits the transcriptional activity of the androgen receptor, known to regulate fatty acid synthesis [2,3]. This compound acts as a cannabin...		Others
T69740	AMG-315
	AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R)-dimethylanandamide. AMG-315 is a high affinity ligand for the ...
T38138	ACEA	2'-chloro-AEA,Arachidonoyl 2'-Chloroethylamide
	Arachidonoyl 2-chloroethylamide (ACEA) is a potent and selective cannabinoid (CB) receptor 1 agonist with Ki values of 1.4 and >2,000 nM for CB1 and CB2 receptors, respectively. In whole animal experiments, ACEA induces ...
T38204	GAT229
	GAT229 is a positive allosteric modulator of cannabinoid receptor 1 (CB1) and the S-(-) enantiomer of the CB1 modulator GAT211. It does not activate the receptor on its own but enhances the binding and activity of CB ago...
T75798	Hemopressin(rat) TFA
	Hemopressin(rat) TFA, a nonapeptide originating from the α1-chain of hemoglobin, was first isolated from rat brain homogenates. It acts as an orally active, selective, and inverse agonist of the CB1 cannabinoid receptors...